610 Main Street, formerly 610 Main Street North, is home to pharmaceutical firm Pfizer and a variety of innovation tenants. The 280,000 square foot multidisciplinary laboratory facility enhances the growing life-science cluster in the Osborn Triangle and Kendall Square area. In addition to Pfizer, the cluster is home to industry leaders such as Novartis and innovation centers including Lab|Central.

Through the creation of public amenities and open space, this new building advances MIT’s interest in improving the innovation environment in Cambridge. It features retail space along Main Street that creates a lively and active urban streetscape, and the Watson Courtyard provides public outdoor space for all to enjoy. In the spirit of creating connections with the community, MIT worked with the Community Art Center (CAC) to create an on-site art installation during construction and offer educational tours and site visits for CAC Teen Media Program students interested in the architecture and construction fields. Further public programming and art installation opportunities are being explored to activate the open space.

With sustainability in mind, 610 Main Street was designed with environmentally responsible features such as electric vehicle charging stations, preferred parking spaces for Low Emitting Fuel Efficient Vehicles, covered bike parking, stormwater mitigation, a reflective roof, water efficient fixtures and irrigation, an energy-conscious design and building envelope, and use of low VOC materials.

Together, 610 Main Street and the One Portland building (formerly known as 610 Main Street South) form a 500,000 square foot LEED-certified research complex.